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WisdomTree Megatrends UCITS ETF - USD Acc

Published 5 August 2025
Head of Research, WisdomTree Europe.
A 90-day pause on US tariffs reignited equity markets in Q2, leading to a strong performance across the board, particularly in the US and Emerging Markets (EM). Thematic equities also benefited with 26 themes out of 42 in the WisdomTree Classification outperforming the MSCI All Country World performance (+11.5%) over the quarter. “Blockchain”, “Nuclear”, “Space”, or “Rise of Tension” (Defence) particularly stood out, with performances flirting or even beating 30% over the quarter.
Overall, thematic equities had one of their strongest quarters in recent years, attracting renewed investor interest. While single themes can deliver strong performance and be used with great effect as satellites in equity portfolios, more and more investors are looking to delegate their thematic investment to an expert by investing in a multi-thematic strategy.
At WisdomTree, our Megatrends Global Equity strategy uses three successive steps to deliver a portfolio designed to capitalise on shifts in the thematic space:
On July 18 2025, the WisdomTree Megatrends Global Equity Index adjusted its tactical positioning based on quantitative momentum and mean reversion signals. These tactical adjustments aim to position the portfolio advantageously, capitalising on themes exhibiting strong momentum while mitigating exposure to areas facing potential headwinds. As thematic equities performed strongly over the period, a few more themes shifted to an overweight position.
Tactical Positioning compared to strategic one (18 July 2025) | |||
|---|---|---|---|
Theme | Positioning | Tactical Signal | Weight |
Aging Population | Underweight | 50% | 2.6% |
Artificial Intelligence & Big Data | Overweight | 150% | 9.0% |
Blockchain | Overweight | 150% | 6.6% |
Cloud Computing | Overweight | 150% | 9.3% |
Cybersecurity | Overweight | 150% | 9.6% |
Digital Infrastructure | Underweight | 50% | 4.1% |
Energy Transition Materials | Underweight | 89% | 4.4% |
HealthTech | Underweight | 50% | 3.6% |
Nuclear | Overweight | 150% | 6.1% |
Quantum Computing | Overweight | 150% | 6.2% |
Rise of China Tech | Overweight | 150% | 8.1% |
Rise of EM Consumer | Overweight | 150% | 4.3% |
Rise of Tension | Overweight | 150% | 7.2% |
Rise of the Middle Class | Underweight | 50% | 2.6% |
Semiconductors | Underweight | 50% | 3.1% |
Sustainable Energy Production | Underweight | 94% | 5.9% |
Sustainable Energy Storage | Underweight | 50% | 5.9% |
Sustainable Food | Underweight | 50% | 5.9% |
For the period from mid-July to mid-October, the portfolio remains overweight in technological and Geopolitical shifts, but the weights are a bit more spread out than in the preceding quarters.

Since the last rebalancing on 22 April 2025, the strategy has outperformed the MSCI All Country World net total return index by 10.64%, having returned 27.7% over the period2.
The source of this outperformance is twofold:
On a relative basis, Quantum Computing contributed the most with a +3.51% added value. Blockchain (+3.2%) and Artificial Intelligence (+2.67%) followed closely, adding to the strategy’s relative performance.
Relative Contribution of Strategic Allocation | Relative Contribution of Tactical Allocation | Relative Contribution of Stock Selection | Total Relative Contribution | |
|---|---|---|---|---|
Total | 10.30% | 1.29% | -0.95% | 10.64% |
Looking back further, the WisdomTree Megatrends Global Equity strategy has returned 55.22% since launch on 27 October 20233. This represents an outperformance of 3.77% compared to the MSCI All Country World.
In contrast to this quarter, the last two years have not been the strongest for thematic equities, characterised by very narrow market breadth and a large domination of market juggernauts. However, tactical overlay and stock selection are the primary sources of strategy outperformance.
Overall, the tactical overweight in Blockchain, Quantum Computing, and Cybersecurity created the most outperformance. Our unique approach to thematic equities, focusing on smaller, more focused stocks, was also successful, with stock selection contributing 2.15% of relative outperformance. Selection in Semiconductors, Sustainable Energy Storage, and Energy Transition Materials was particularly impactful.
Relative Contribution of Strategic Allocation | Relative Contribution of Tactical Allocation | Relative Contribution of Stock Selection | Total Relative Contribution | |
|---|---|---|---|---|
Total | -5.75% | 6.74% | 2.15% | 3.2% |
Almost two years since its launch, the Megatrends Strategy continues to create value compared to the market benchmark and its large peers in the space. European Defence, Quantum Computing, Nuclear, Blockchain and Cybersecurity are five themes with clear macro tailwinds and are WisdomTree’s high-conviction thematic ideas for the remainder of 2025 and beyond. The WisdomTree Megatrends strategy is currently overweighted in all five, delivering a very differentiated exposure.
1Guiding and Establishing National Innovation for US Stablecoins
2Source: WisdomTree, Bloomberg. In USD. From 22 April 2025 to 18 July 2025. You cannot invest directly in an index. Historical performance is not an indication of future performance and any investments may go down in value.
3Source: WisdomTree, Bloomberg. In USD. From 27 October 2023 top 18 July 2025. You cannot invest directly in an index. Historical performance is not an indication of future performance and any investments may go down in value.

Head of Research, WisdomTree Europe.
Pierre Debru leads WisdomTree’s European research team and plays a pivotal role in the strategic direction of our European research efforts. His key areas of expertise extend across equity factors and quantitative strategies, portfolio construction and model portfolios, and thematic and crypto investments. Before joining the company in 2019, Pierre worked in Investment Research for DWS and the Xtrackers range for over five years. During this period, he focused on smart beta investments, model portfolio construction and thought leadership. Pierre has over 20 years of experience in investments and structured asset management. He graduated from Ecole Central Paris and obtained a Master of Science in Mathematics applied to Finance.